鄭財木(Cheng, Tsai-Mu) 副教授

Email
tmcheng@tmu.edu.tw
現   職
轉譯醫學博士學位學程 副教授

學經歷

學 歷

畢業學校與學位[修業時間]
交通大學生物科技 博士
2001/09~2008/06
陽明大學生物化學 碩士
1995/09~1998/12
東海大學環境科學 學士
1987/09~1991/06

本校學術經歷

任職單位與職稱[起迄時間]
轉譯醫學博士學位學程副教授
2018/02/01~
轉譯醫學博士學位學程助理教授
2013/10/30~2018/01/31
轉譯醫學博士學位學程助理研究員
2012/08/01~2013/10/29

本校兼職教學行政經歷

服務單位與職稱[起迄時間]
國際轉譯科學博士學位學程籌備處副教授
2020/05/01 ~
醫學資訊研究所助理教授
2017/03/01 ~

其它經歷

任職單位與職稱[起迄時間]
加拿大國家科學研究院訪問學者
2009/12~2011/01
交通大學博士後研究
2008/08~2012/07
元培科技大學講師
2004/07~2006/01
台北榮總研究助理
1999/01~1998/07
動科研究所研究助理
1993/09~1995/09

專長與研究領域

學門領域
醫學之生化及分子生物
生物學之生化及分子生物
學術專長

論文著作

清冊下載


1. 2020 Tang KY,, Huang SY, ,Cheng TM, ,Bai CH, ,Chang JS.. Haptoglobin phenotype influences the effectiveness of diet-induced weight loss in middle-age abdominally obese women with metabolic abnormalities. . Clin Nutr. .2020 ;(39):225-233

2. 2020 Lin CC,Chang WH,Cheng TM,Chiu LH,Wang YH,Lin CJ, Ho YS, Zuo CS, Wang YM, Lai WT.. Two new, near-infrared, fluorescent probes as potential tools for imaging bone repair. . Sci Rep. .2020 ;(10):2580

3. 2020 Hsu MH,, Hsieh CY, ,Kapoor M,, Chang JH,, Chu HL, ,Cheng TM, Hsu KC, Lin TE, Tsai FY, Horng JC. Leucettamine B analogs and their carborane derivative as potential anti-cancer agents: Design, synthesis, and biological evaluation. . Bioorg Chem .2020 ;(98):103729.

4. 2020 Chew CH,,Lee CW, ,Huang WT, ,Cheng LW, ,Chen A, ,Cheng TM, Liu YL, Chen CC. . Microtube Array Membrane (MTAM)-Based Encapsulated Cell Therapy for Cancer Treatment. . Membranes .2020 ;(10)

5. 2020 Cheng TM, ,Li R, ,Kao YC Jill, ,Hsu CH, ,Chu HL, ,Lu KY, Changou CA, Chang CC, Chang LH,Tsai, Mi FL.. Synthesis and characterization of Gd-DTPA/fucoidan/peptide complex nanoparticle and in vitro magnetic resonance imaging of inflamed endothelial cells. . Materials Science & Engineering C. .2020

6. 2020 Yougbaré S, ,Mutalik C, ,Krisnawati DI, ,Kristanto H, ,Jazidie A, ,Nuh M, Cheng TM*, Kuo TR*. . Nanomaterials for the Photothermal Killing of Bacteria. . Nanomaterials. .2020 ;(10):E1123.-E1123.

7. 2019 Lee PL,Lee KY ,Cheng TM ,Chuang HC ,Wu SM ,Feng PH, Liu WT, Chen KY, Ho SC. Relationships of Haptoglobin Phenotypes with Systemic Inflammation and the Severity of Chronic Obstructive Pulmonary Disease . Scientific Reports .2019 ;(9):189

8. 2019 Chang TK,Cheng TM* ,Chu HL ,Tan SH ,Kuo JC ,Hsu PH, Su CY, Chen HM, Lee CM, Kuo TR. Metabolic Mechanism Investigation of Antibacterial Active Cysteine-Conjugated Gold Nanoclusters in Escherichia coli. . ACS Sustainable Chemistry & Engineering .2019 ;(7):15479-15486

9. 2018 Cheng TM,Chu HL,Lee YC,Wang DY,Chang CC,Chung KL, Yen HC, Hsiao CW, Pan XY, Kao TR, Chen CC.. Quantitative Analysis of Glucose Metabolic Cleavage in Glucose Transporters Overexpressed Cancer Cells by Target-Specific Fluorescent Gold Nanoclusters. . Anal Chem .2018 ;(90):3974-3980

10. 2018 Nana AW,Wu SY, Yang YS,Chin YT,Cheng TM,Ho Y, Li WS, Liao YM, Chen YR, Shih YJ, Liu YR, Pedersen J, Incerpi S, Hercbergs A, Liu LF, Whang-Peng J, Davis PJ, Lin HY. Nano-Diamino-Tetrac (NDAT) Enhances Resveratrol-Induced Antiproliferation by Action on the RRM2 Pathway in Colorectal Cancers. . Horm Cancer. .2018 ;(9):349-360

11. 2018 Lu DY, Lin CP,Wu CH,Cheng TM ,Pan JP. Plasma haptoglobin level can augment NT-proBNP to predict poor outcome in patients with severe acute decompensated heart failure. . J Investig Med. .2018

12. 2018 Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) promotes EGF receptor signaling of oral squamous cell carcinoma metastasis via the complex N-glycosylation. . Oncogene. .2018 ;(37):116-127

13. 2017 Cheng TM, Chin YT,Ho Y,Chen YR,Yang YN, Yang YC, Shih YJ, Lin TI, Lin HY, Davis PJ.. Resveratrol Induces Sumoylated COX-2-dependent Anti-proliferation in Human Prostate Cancer LNCaP Cells . Food and Chemical Toxicology. .2017 ;(112):67-75

14. 2017 Wu MH,Chen YL,Lee KH, Chang CC ,Cheng TM ,Wu SY, Tu CC, Tsui WL. . Glycosylation-dependent galectin-1/neuropilin-1 interactions promote liver fibrosis through activation of TGF-β- and PDGF-like signals in hepatic stellate cells . Scientific Reports .2017 ;(7):11006

15. 2017 Chiang KH ,Kao YT ,Leu HB ,Huang PH, Huang SS,,Cheng TM, Pan JP.. Higher post-acute myocardial infarction plasma haptoglobin level is associated with poor long-term overall survival . International Journal of Cardiology .2017 ;(229):102-107

16. 2017 Lu KY,Lin PY,Chuang EY,Shih CM,Cheng TM,Lin TY, Sung HW, Mi FL. H2O2-Depleting and O2-Generating Selenium Nanoparticles for Fluorescence Imaging and Photodynamic Treatment of Proinflammatory-Activated Macrophages. . ACS Appl Mater Interfaces .2017 ;(9):5158-5172

17. 2014 Hsueh-Liang Chu,Tzu-Hsuan Chen,Chang-You Wu,Yao-Chen Yang,Shin-Hua Tseng,Tsai-Mu Cheng, Li-Ping Ho, Li-Yun Tsai, Hsing-yuan Li, Chia-Seng Chang, Chia-Ching Chang. Thermal stability and folding kinetics analysis of disordered protein, securin . J Therm Anal Calorim .2014

18. 2014 Tsai-Mu Cheng,Yanal M. Murad,Chia-Ching Chang,Ming-Chi Yang,Toya Nath Baral,Aaron Cowan, Shin-Hua Tseng, Andrew Wong, Roger MacKenzie, Dar-Bin Shieh, Jianbing Zhang. Single domain antibody against carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) inhibits proliferation, migration, invasion and angiogenesis of pancreatic cancer cells. . European Journal of Cancer .2014 ;(50):713-721

19. 2014 Hsueh-Liang Chu,Hung-Wei Chen,Shin-Hua Tseng,Ming-Hua Hsu,Li-Ping Ho,Fu-Hsuan Chou, Hsing-Yuan Li, Yu-Chuan Chang, Pei-Hsin Chen......Tsai-Mu Cheng*, Chia-Ching Chang. Development of a Growth-Hormone-Conjugated Nanodiamond Complex for Cancer Therapy . CHEMMEDCHEM .2014 ;(9):1023-1029

20. 2013 Li HY,Tseng SH,Cheng TM,Chu HL,Lu YN,Wang FY, Tsai LY, Shieh JY, Yang JY, Juan CC, Tu LC, Chang CC.. Rapid and highly sensitive detection of Enterovirus 71 by using nanogold-enhanced electrochemical impedance spectroscopy. . Nanotechnology. .2013 ;(24):285102

21. 2013 Chu HL,*Cheng TM,Chen HW,Chou FH,Chang YC,Lin HY, Liu SY, Liang YC, Hsu MH, Wu DS, Li HY, Ho LP, Wu PC, Chen FR, Chen GS, Shieh DB, Chang CC. Synthesis of Apolipoprotein B Lipoparticles to Deliver Hydrophobic/Amphiphilic Materials. . ACS Appl Mater Interfaces. .2013 ;(Co-1st)

22. 2013 Lee CW,Cheng TM,Lin CP,Pan JP. Plasma Haptoglobin Concentrations Are Elevated in Patients with Coronary Artery Disease. . PLoS One .2013 ;(8):e76817

23. 2011 Cheng TM,Mao SJT,Lai ST,Chang CC,Yang MC,Chen NC, Chou SC, Pan JP. Haemoglobin-induced oxidative stress is associated with both endogenous peroxidase activity and H2O2 generation from polyunsaturated fatty acids. . Free Radic Res .2011 ;(45):303-316

24. 2011 Pan JP,Cheng TM,Shih CC,Chiang SC,Chou SC,Mao SJ, Lai ST. Haptoglobin phenotypes and plasma haptoglobin levels in patients with abdominal aortic aneurysm. . J Vasc Surg. .2011 ;(53):1189-1194

25. 2011 Tseng SH,JangJian PC,Tsai CM,Cheng TM,Chu HL,Chang YC, Chung WH, Chang CC. Ni2+-enhanced charge transport via π-π stacking corridor in metallic DNA. . Biophys J. .2011 ;(100):1042-1048

26. 2011 Cheng TM,Lee TC,Tseng SH,Chu HL,Pan JP,Chang CC. Human haptoglobin phenotypes and concentration determination by nanogold-enhanced electrochemical impedance spectroscopy. . Nanotechnology. .2011 ;(22):245105

27. 2010 JangJian PC,Tseng SH,Tsai CM,Cheng TM,Chu HL,Chang CC. DNA: a native nano-wire in nature. . Instruments Today. .2010 ;(31):61-71

28. 2009 Jangjian PC,Liu TF,Tsai CM,Li MY,Tsai MS,Tseng SH, Cheng TM, Chang CC. DNA Mismatch Detection by Metal Ion Enhanced Impedance Analysis . CHINESE JOURNAL OF PHYSICS .2009 ;(47):740-747

29. 2007 Cheng TM,Huang PC,Pan JP,Lin KY,Mao SJ. Gel electrophoresis of polyphenol oxidase with instant identification by in situ blotting. . J Chromatogr B Analyt Technol Biomed Life Sci .2007 ;(849):331-336

30. 2007 Cheng TM,Pan JP,Lai ST,Kao LP,Lin HH,Mao SJT. Immunochemical property of human haptoglobin phenotypes: determination of plasma haptoglobin using type-matched standards. . Clin Biochem. .2007 ;(40):1045-56

31. 2003 Liau CY,Chang TM,Pan JP,Cheng WL,Mao SJT. P urification of human plasma haptoglobin by hemoglobin-affinity column chromatography . Journal of Chromatography B .2003 ;(790):209-216

32. 2003 Pan JP,Cheng TM,Chou SC,Lai ST. Vitamin C protects against lysophosphatidylcholine-induced expression of monocyte chemoattractant protein-1 in cultured human umbilical vein endothelial cells. . J Formos Med Assoc. .2003 ;(102):151-157


1. 2017 Tsai-Mu Cheng, ,Hsueh-Liang Chu, ,Ju-Pin Pan. Haptoglobin prevents atherosclerosis by inflammation regulation: A prevention role of haptoglobin Hp for atherosclerosis. . The FASEB Journal .2017 ;(31):825.1


1. 2013 Larsson M,Cheng TM,Chen CY,Mao SJT. Unique Assembly Structure of Human Haptoglobin Phenotypes 1-1, 2-1, and 2-2 and a Predominant Hp 1 Allele Hypothesis . INTECH. Acute Phase Proteins. Chapter 7. ISBN 978-953-51-1185-6 .2013

研究計畫

計畫名稱
107 血紅素結合蛋白當冠狀動脈心臟病之蛋白質體藥評估
補助單位
科技部

計畫名稱
105 不同表現型之血紅素結合蛋白在缺血性心臟病之功能差異及其重組次單元當缺血性心臟病胜?藥評估
補助單位

計畫名稱
104 血紅素結合蛋白及其次單元當缺血性心臟病蛋白質藥的評估
補助單位
科技部

計畫名稱
104 親血球蛋白胜肽改善心肌梗塞之藥物研發評估
補助單位
新光醫療財團法人新光吳火獅紀念醫院

計畫名稱
102 TMU102-AE1-B36
補助單位
臺北醫學大學新聘教師計畫