謝嘉玲(Hsieh, Chia-Ling) 副教授

Email
chsieh2@tmu.edu.tw
現   職
國際轉譯科學博士學位學程籌備處 主任
轉譯醫學博士學位學程 主任
轉譯醫學博士學位學程 副教授

學經歷

畢業學校與學位[修業時間]
台灣大學微生物學研究所 博士
1993/09~1998/12
台灣大學醫事技術學研究所 碩士
1989/09~1991/06
台灣大學醫事技術學系 學士
1985/09~1989/06

本校學術經歷

任職單位與職稱[起迄時間]
轉譯醫學博士學位學程副教授
2013/08/01~

本校行政經歷

服務單位與職稱[起迄時間]
醫學資訊研究所副教授
2019/11/01 ~
國際轉譯科學博士學位學程籌備處主任
2019/10/01 ~
轉譯醫學博士學位學程主任
2018/08/01 ~
細胞治療與再生醫學國際博士學位副教授
2018/02/01 ~

其它經歷

任職單位與職稱[起迄時間]
中國醫藥大學副教授
2007/08/01~2013/07/31

專長與研究領域

學門領域
生物學之生化及分子生物
醫學之生化及分子生物
泌尿科
學術專長

論文著作

清冊下載

論文 Journal Paper
2019 Chu‐Lun Lin,Huei‐Mei Huang,Chia‐Ling Hsieh,Chia‐Kwung Fan,Yueh‐Lun Lee. Jagged1-expressing adenovirus-infected dendritic cells induce expansion of Foxp3+ regulatory T cells and alleviate T helper type 2-mediated allergic asthma in mice . Immunology .2019 ;(156):199-212


論文 Journal Paper
2019 Sun CQ,Arnold RS,Hsieh CL,Dorin JR,Lian F,Li Z, Petros JA. Discovery and mechanisms of host defense to oncogenesis: targeting the β-defensin-1 peptide as a natural tumor inhibitor . Cancer Biol Ther. .2019 ;(20):774-786


論文 Journal Paper
2019 Chu GC,Chung LWK,Gururajan M,Hsieh CL,Josson S,Nandana S, Sung SY, Wang R, Wu JB, Zhau HE. Regulatory signaling network in the tumor microenvironment of prostate cancer bone and visceral organ metastases and the development of novel therapeutics . Asian J Urol .2019 ;(6):65-81


論文 Journal Paper
2019 Hsu FT,Sun R,Hsieh CL. Cellular Magnetic Resonance Imaging with Superparamagnetic Iron Oxide: Methods and Applications in Cancer . SPIN .2019 ;(9):1940007-1-1940007-10


論文 Journal Paper
2019 Hsieh CL,Huang HS,Chen KC,Saka, T,Chiang CY,Chung WKL, Sung YL. A Novel Salicylanilide Derivative Induces Autophagy Cell Death in Castration-Resistant Prostate Cancer Via ER Stress-Activated PERK Signaling Pathway . Molecular Cancer Therapeutics .2019 ;(Epub ahead of print):1-11


論文 Journal Paper
2019 Wang HJ,Pochampalli M,Wang LY,Zou JX,Li PS,Hsu SC, Wang BJ, Huang SH, Yang P, Yang JC, Chu CY, Hsieh CL, Sung SY, Li CF, Tepper CG, Ann D K, Gao AC, Evans CP, Izumiya Y, Chuu CP, Wang WC, Chen HW, Kung HJ. KDM8/JMJD5 as a dual coactivator of AR and PKM2 integrates AR/EZH2 network and tumor metabolism in CRPC . Oncogene .2019 ;(38):17-32


論文 Journal Paper
2018 Hsu FT,Wei ZH,Hsuan YC, Lin W,Su YC, Liao CH, Hsieh CL. MRI tracking of polyethylene glycol-coated superparamagnetic iron oxide-labelled placenta-derived mesenchymal stem cells toward glioblastoma stem-like cells in a mouse model . Artificial cells, nanomedicine, and biotechnology .2018 ;(Epub ahead of print):1-12


論文 Journal Paper
2018 Yen TH,Hsieh CL,Liu TT,Huang CS,Chen YC,Chuang YC, Lin SS, Hsu FT. Amentoflavone Induces Apoptosis and Inhibits NF-kB-modulated Anti-apoptotic Signaling in Glioblastoma Cells . In Vivo .2018 ;(無):279-285


論文 Journal Paper
2017 Hsieh CL,Liu CM,Chen HA,Yang ST,Shigemura K,Kitagawa K, Yamamichi, F, Fujisawa M, Liu, YR, Lee WH, Chen KC, Shen CN, Lin CC, Chung L, Sung SY. Reactive oxygen species–mediated switching expression of MMP-3 in stromal fibroblasts and cancer cells during prostate cancer progression . Scientific Reports .2017 ;(7):9065-9065


論文 Journal Paper
2017 Chen WL,Hsieh CL,Chen JH,Huang CS,Chen WT,Kuo YC, Chen CY, Hsu FT. Amentoflavone enhances sorafenib‑induced apoptosis through extrinsic and intrinsic pathways in sorafenib‑resistant hepatocellular carcinoma SK‑Hep1 cells in vitro . ONCOLOGY LETTERS .2017 ;(14):3229-3234


論文 Journal Paper
2016 Liu CM,Hsieh CL,Shen CN,Lin CC,Shigemura K,Sung SY. Exosomes from the tumor microenvironment as reciprocal . international journal of Urology .2016 ;(23):734-744


論文 Journal Paper
2016 Sung SY,Chang JL,Ken KC,Yeh SD,Liu YR,Su YH, Chung Leland, Hsieh CL. Co-Targeting Prostate Cancer Epithelium and . PLOS ONE .2016 ;(11):e01533-e01533


論文 Journal Paper
2016 Ali AA,Hsu FT,Hsieh CL,Shiau CY,Chiang CH,Wei ZH, Chen CY, Huang HS. Erlotinib-Conjugated Iron Oxide Nanoparticles as a Smart Cancer-Targeted Theranostic Probe for MRI . Scientific Reports .2016 ;(6):36650-36650


論文 Journal Paper
2015 Shih JW,Wang LY,Hung CL,Kung HK,Hsieh CL. Non-Coding RNAs in Castration-Resistant Prostat eCancer: Regulation of Androgen Receptor Signaling and Cancer Metabolism . International Journal of Molecular Science .2015 ;(16):28943-28978


論文 Journal Paper
2014 Sung SY,Wu IH,Chuang PH,Petros JA,Wu HC,Zeng, HJ, Huand, WC, Chung LWK, Hsieh CL. Targeting L1 cell adhesion molecule expression using liposome encapsulated siRNA suppresses prostate cancer bone metastasis . Oncotarget .2014 ;(5):9911-9929


論文 Journal Paper
2014 Wu K,Liu J,Tseng SF,Gore C,Ning Z,Sharifi N, Fazli L, Gleave M, Kapur P, Xiao G, Sun X, Oz OK,Win W, Alexandrakis G, Yang CR, Hsieh CL. The role of DAB2IP in androgen receptor activation during prostate cancer progression. . Oncogene .2014 ;(33):1954-1963


論文 Journal Paper
2013 Sung SY,Liao CH,Wu HP,Hsiao WC,Wu IH,Yu J, Lin SH, Hsieh CL. Loss of Let-7 microRNA upregulates IL-6 in bone marrow-derived mesenchymal stem cells triggering a reactive stromal response to prostate cancer . PLOS ONE .2013 ;(8):e71637-e71637


論文 Journal Paper
2013 Liu CM, Hsieh CL,He YC,Lo SJ,Liang JA,Hsieh TF,Hsieh TF, Josson S, Chung LW, Hung MC, Sung SY. In vivo targeting of ADAM9 gene expression using lentivirus-delivered shRNA suppresses prostate cancer growth by regulating REG4 dependent cell cycle progression . PLOS One .2013 ;(8):e53795-e53795


論文 Journal Paper
2012 Hsiao WC,Sung SY,Liao CH,Wu HC,Hsieh CL. Vitamin d(3)-inducible mesenchymal stem cell-based delivery of conditionally replicating adenoviruses effectively targets renal cell carcinoma and inhibits tumor growth . Molecular Pharmapeutics .2012 ;(9):1396-1408


論文 Journal Paper
2011 Josson S,Anderson CS,Sung SY,Johnstone PA,Kubo H,Hsieh CL, Arnold R, Gururajan M, Yates C, Chung LW. Inhibition of ADAM9 expression induces epithelial phenotypic alterations and sensitizes human prostate cancer cells to radiation and chemotherapy . Prostate .2011 ;(71):232-240


論文 Journal Paper
2010 Hung SC,Wu IH,Hsue SS,Liao CH,Wang HC,Chuang PH, Sung SY, Hsieh CL. Targeting L1 Cell Adhesion Molecule Using Lentivirus-Mediated Short Hairpin RNA Interference Reverses Aggressiveness of Oral Squamous Cell Carcinoma . Molecular Pharmaceutics .2010 ;(7):2312-2323


論文 Journal Paper
2010 Johnson AN,Chen BH,Sung SY,Liao CH,Hsiao WC,Chung LW, Hsieh CL. A novel targeting modality for renal cell carcinoma: human osteocalcin promoter-mediated gene therapy synergistically induced by vitamin C and vitamin D3. . Journal of Gene Medicine .2010 ;(12):892-903


論文 Journal Paper
2009 Shi C,Zhu Y,Xie Z,Qian W,Hsieh CL,Nie S, Su Y, Zhau HE, Chung LW. Visualizing human prostate cancer cells in mouse skeleton using bioconjugated near-infrared fluorescent quantum dots . Urology .2009 ;(74):446-451


論文 Journal Paper
2009 Arnold R S,Sun CQ,Richards JC,Grigoriev G,Coleman IM,Nelson PS, Hsieh CL, Lee JK, Xu Z, Rogatko A, Osunkoya AO, Zayzafoon M, Chung L, Petros JA. Mitochondrial DNA mutation stimulates prostate cancer growth in bone stromal environment . Prostate .2009 ;(69):1-11


書籍 Book
2019 Hsiao WC,Sung SY,Chung LWK,Hsieh CL. Osteonectin Promoter-Mediated Suicide Gene Therapy of Prostate Cancer . Methods in Molecular Biology .2019 ;(1895):27-42

研究計畫

計畫名稱
107 探討細胞吸附因子L1CAM在神經內分泌前列腺癌進展的角色
補助單位
科技部

計畫名稱
106 細胞吸附分子L1CAM 在轉移性去勢療法無效前列腺癌的分子與轉譯研究
補助單位
科技部

計畫名稱
105 探討骨髓間質幹細胞在前列腺癌引發的骨重塑的生物功能與作用機制(3/3)
補助單位
科技部

計畫名稱
105 探討骨髓間質幹細胞在前列腺癌引發的骨重塑的生物功能與作用機制(3/3)
補助單位
科技部

計畫名稱
104 探討骨髓間質幹細胞在前列腺癌引發的骨重塑的生物功能與作用機制(2/3)
補助單位
科技部

計畫名稱
104 探討骨髓間質幹細胞在前列腺癌引發的骨重塑的生物功能與作用機制(2/3)
補助單位
科技部

計畫名稱
103 子計畫三:實驗探討人類胎盤間質幹細胞對早產兒腦傷及慢性肺病變和腦瘤幹細胞的治療效果
補助單位
宣捷生物科技股份有限公司

計畫名稱
103 探討骨髓間質幹細胞在前列腺癌引發的骨重塑的生物功能與作用機制(1/3)
補助單位
科技部

計畫名稱
103 探討骨髓間質幹細胞在前列腺癌引發的骨重塑的生物功能與作用機制(1/3)
補助單位
科技部

計畫名稱
102 發展一根據MICRORNA調控腫瘤微環境為機理的基因治療策略來治療前列腺癌骨轉移
補助單位
科技部

計畫名稱
102 TMU102-AE1-B16
補助單位
學校

計畫名稱
101 發展一根據microRNA調控腫瘤微環境為機理的基因治療策略來治療前列腺癌骨轉移
補助單位
行政院國家科學委員會