| 1. |
2020
Chen TC#,Chuang JY#,Ko CY,Kao TJ,Yang PY,Yu CH, Liu MS, Hu SL, Tsai YT, Chan H, Chang WC*, Hsu TI*.
AR ubiquitination induced by the curcumin analog suppresses growth of temozolomide-resistant glioblastoma through disrupting GPX4-Mediated redox homeostasis
. Redox Biol
.2020
;(30):101413-101413
|
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| 2. |
2020
Huang YH,Wu YW,Chuang JY,Chang YC,Chang HF,Tao PL, Loh HH, Yeh SH*.
Morphine produces potent antinociception, sedation, and hypothermia in humanized mice expressing human mu-opioid receptor splice variants.
. Pain
.2020
|
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| 3. |
2020
Limanjaya I,Hsu TI,Chuang JY,Kao TJ*.
L-selectin activation regulates Rho GTPase activity via Ca+2 influx in Sertoli cell line, ASC-17D cells
. Biochem Biophys Res Commun
.2020
|
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| 4. |
2020
Lo WL,Hsu TI,Yang WB,Kao TJ,Wu MH,Huang YN, Yeh SH, Chuang JY*.
Betulinic acid-mediated tuning of PERK/CHOP signaling by Sp1 inhibition as a novel therapeutic strategy for glioblastoma
. Cancers
.2020
;(12)
|
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| 5. |
2020
Yang WB,Hsu CC,Hsu TI,Liou JP,Chang KY,Chen PY, Liu JJ, Yang ST, Wang JY, Yeh SH, Chen RM, Chang WC*, Chuang JY*.
Increased activation of HDAC1/2/6 and Sp1 underlies therapeutic resistance and tumor growth in glioblastoma
. Neuro-Oncology
.2020
;(22):1439-1451
|
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| 6. |
2020
Hung HC,Liu CC,Chuang JY,Su CL,Gean PW.
Inhibition of Sonic Hedgehog Signaling Suppresses Glioma Stem-Like Cells Likely Through Inducing Autophagic Cell Death
. Front Oncol
.2020
;(10):1233
|
|
| 7. |
2020
Lee PT,Lievens JC,Wang SM,Chuang JY,Khalil B,Wu HE, Chang WC, Maurice T, Su TP*.
Sigma-1 receptor chaperones rescue nucleocytoplasmic transport deficit seen in cellular and Drosophila ALS/FTD models
. Nature Communications
.2020
;(11):5580
|
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| 8. |
2020
Chao PK,Chang HF,Chang WT,Yeh TK,Ou LC,Chuang JY, Tsu-An Hsu J, Tao PL, Loh HH, Shih C, Ueng SH, Yeh SH.
BPR1M97, a dual mu opioid receptor/nociceptin-orphanin FQ peptide receptor agonist, produces potent antinociceptive effects with safer properties than morphine.
. Neuropharmacology
.2020
;(166):107678
|
|
| 9. |
2020
Hung CY,Hsu TI,Chuang JY,Su TP,Chang WC,Hung JJ*.
Sp1 in Astrocyte Is Important for Neurite Outgrowth and Synaptogenesis
. Mol Neurobiol
.2020
;(57):261-277
|
|
| 10. |
2019
Lin HY,Ko CY,Kao TJ,Yang WB,Tsai YT,Chuang JY, Hu SL, Yang PY, Lo WL, Hsu TI*.
CYP17A1 Maintains the Survival of Glioblastomas by Regulating SAR1-Mediated Endoplasmic Reticulum Health and Redox Homeostasis
. Cancers (Basel)
.2019
;(11):pii: E1378
|
|
| 11. |
2019
Chien CH,Chuang JY,Yang ST,Yang WB,Chen PY,Hsu TI, Huang CY, Lo WL, Yang KY, Liu MS, Chu JM, Chung PH, Liu JJ, Chou SW, Chen SH, Chang KY*.
Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets
. J Biomed Sci
.2019
;(26):77
|
|
| 12. |
2019
Tsai YT,Wu AC,Yang WB,Kao TJ,Chuang JY,Chang WC*, Hsu TI*.
ANGPTL4 Induces TMZ Resistance of Glioblastoma by Promoting Cancer Stemness Enrichment via the EGFR/AKT/4E-BP1 Cascade
. Int J Mol Sci
.2019
;(20):pii: E5625
|
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| 13. |
2019
Chao PK,Chang HF,Ou LC,Chuang JY,Lee PT,Chang WT, Chen SC, Ueng SH, Hsu JT, Tao PL, Law PY, Loh HH, Yeh SH*.
Convallatoxin enhance the ligand-induced mu-opioid receptor endocytosis and attenuate morphine antinociceptive tolerance in mice
. Sci Rep
.2019
;(9):2405
|
|
| 14. |
2019
Wang SM,Lin HY,Chen YL,Hsu TI,Chuang JY,Kao TJ, Ko CY*.
CCAAT/enhancer-binding protein delta regulates the stemness of glioma stem-like cells through activating PDGFA expression upon inflammatory stimulation
. J Neuroinflammation
.2019
;(16):146
|
|
| 15. |
2018
Chio CC,Chen KY,Chang CK,Chuang JY ,Liu CC,Liu SH, Chen RM.
Improved effects of honokiol on temozolomide-induced autophagy and apoptosis of drug-sensitive and -tolerant glioma cells
. BMC Cancer
.2018
;(18)
|
|
| 16. |
2018
Chang CJ,Chang MY,Chou SY,Huang CC,Chuang JY,Hsu TI, Chang HF, Wu YH, Wu CC, Morales D, Kania A, Kao TJ.
Ephexin1 is required for Eph-Mediated limb trajectory of spinal motor axons
. Journal of Neuroscience
.2018
;(38):2043-2056
|
|
| 17. |
2018
Ko CY,Lin CH,Chuang JY,Chang WC,Hsu TI.
MDM2 Degrades Deacetylated Nucleolin Through Ubiquitination to Promote Glioma Stem-Like Cell Enrichment for Chemotherapeutic Resistance
. Molecular Neurobiology
.2018
;(55):3211-3223
|
|
| 18. |
2018
Lin CY,Yang ST,Shen SC,Hsieh YC,Hsu FT,Chen CY, Chiang YH, Chuang JY, Chen KY, Hsu TI, Leong WC, Su YK, Lo WL, Yeh YS, Patria YN, Shih HM, Chang CC, Chou SY.
Serum amyloid A1 in combination with integrin αVβ3 increases glioblastoma cells mobility and progression
. Molecular Oncology
.2018
;(12):756-771
|
|
| 19. |
2018
Chang CJ,Chang MY,Lee YC,Chen KY,Hsu TI,Wu YH, Chuang JY*, Kao TJ*.
Nck2 is essential for limb trajectory selection by spinal motor axons
. Developmental Dynamics
.2018
;(247):1043-1056
|
|
| 20. |
2018
Yang WB,Chuang JY,Ko CY,Chang WC,Hsu TI.
Dehydroepiandrosterone induces temozolomide resistance through modulating phosphorylation and acetylation of Sp1 in glioblastoma
. Mol Neurobiol
.2018
|
|
| 21. |
2018
Wu CC,Lee PT,Kao TJ,Chou SY,Su RY,Lee YC, Yeh SH, Liou JP, Hsu TI, Su TP, Chuang CK, Chang WC*, Chuang JY*.
Upregulation of Znf179 acetylation by SAHA protects cells against oxidative stress
. Redox Biol
.2018
;(19):74-80
|
|
| 22. |
2017
Chang KY,Huang CT,Hsu TI,Hsu CC,Liu JJ,Chuang CK, Hung JJ, Chang WC, Tsai KK, Chuang JY*.
Stress stimuli induce cancer-stemness gene expression via Sp1 activation leading to therapeutic resistance in glioblastoma.
. Biochem Biophys Res Commun
.2017
;(493):14-19
|
|
| 23. |
2017
Chuang JY,Kao TJ,Lin SH,Wu AC,Lee PT,Su TP, Yeh SH, Lee YC, Wu CC, Chang WC.
Specificity protein 1-zinc finger protein 179 pathway is involved in the attenuation of oxidative stress following brain injury
. Redox Biology
.2017
;(11):135-143
|
|
| 24. |
2017
Ke YY,Huang YH,Chien WC,Loh HH,Chuang JY*,Yeh SH*.
Mapping the naloxone binding sites on the mu-opioid receptor using cell-based photocrosslinkers
. Biochim Biophys Acta
.2017
;(1865):336-343
|
|
| 25. |
2017
Chao PK,Ueng SH,Ou LC,Yeh TK,Chang WT,Chang HF, Chen SC, Tao PL, Law PY, Loh H, Cheng MF, Chuang JY, Chen CT, Shih C, Yeh SH.
1-(2,4-Dibromophenyl)-3,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indazol-4-one: A Novel Opioid Receptor Agonist with Less Accompanying Gastrointestinal Dysfunction than Morphine.
. Anesthesiology
.2017
;(126):952-966
|
|
| 26. |
2017
Chuang JY,Lo WL,Ko CY,Chou SY,Chen RM,Chang KY, Hung JJ, Su WC, Chang WC*, Hsu TI*..
Upregulation of CYP17A1 by Sp1-mediated DNA Demethylation Confers Temozolomide Resistance through DHEA-Mediated Protection in Glioma.
. Oncogenesis
.2017
;(6):e339
|
|
| 27. |
2017
Chang KY,Hsu TI,Hsu CC,Tsai SY,Liu JJ,Chou SW, Liu MS, Liou JP, Ko CY, Chen KY, Hung JJ, Chang WC, Chuang CK, Kao TJ, Chuang JY.
Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O6-methylguanine-DNA methyltransferase
. Redox Biol
.2017
;(13):655-664
|
|
| 28. |
2017
Hung CY,Wang YC,Chuang JY,Young MJ,Liaw H,Chang WC, and Hung JJ.
Nm23-H1-stabilized hnRNPA2/B1 promotes internal ribosomal entry site (IRES)-mediated translation of Sp1 in the lung cancer progression
. Sci Rep
.2017
;(7):9166
|
|
| 29. |
2016
Su TC,Lin SH,Lee PT,Yeh SH,Hsieh TH,Chou SY, Su, TP Hung JJ, Chang WC, Lee YC*, Chuang JY*.
The sigma-1 receptor-Zinc finger protein 179 pathway protects against hydrogen peroxide-induced cell injury
. Neuropharmacology
.2016
;(105):1-9
|
|
| 30. |
2016
Hsu CC,Chang WC,Hsu TI,Liu JJ,Yeh SH,Wang JY, Liou JP, Ko CY, Chang KY, Chuang JY.
Suberoylanilide hydroxamic acid represses glioma stem-like cells
. Journal of Biomedical Science
.2016
;(23):81
|
|
| 31. |
2015
Tsai SA#,Chuang JY#,Tsai MS,Wang XF,Xi ZX,Hung JJ, Chang WC, Bonci A, Su TP*.
Sigma-1 receptor mediates cocaine-induced transcriptional regulation by recruiting chromatin-remodeling factors at the nuclear envelope.
. Proc Natl Acad Sci U S A
.2015
;(112):E6562-E6570
|
|
| 32. |
2014
Wang SA,Hung CY,Chuang JY,Chang WC,Hsu TI,Hung JJ.
Phosphorylation of p300 increases its protein degradation to enhance the lung cancer progression
. Biochim Biophys Acta
.2014
;(1843):1135-1149
|
|
| 33. |
2014
Lee PT,Chao PK,Ou LC,Chuang JY,Lin YC,Chen SC, Chang HF, Law PY, Loh HH, Chao YS, Su TP, Yeh SH*.
Morphine drives internal ribosome entry site-mediated hnRNP K translation in neurons through opioid receptor-dependent signaling.
. Nucleic Acids Res
.2014
;(42):13012-13025
|
|
| 34. |
2014
Yang HC,Chuang JY,Jeng WY,Liu CI,Wang AH,Lu PJ, Chang WC, Hung JJ*.
Pin1-mediated Sp1 phosphorylation by CDK1 increases Sp1 stability and decreases its DNA-binding activity during mitosis.
. Nucleic Acids Res
.2014
;(42):13573-13587
|
|
| 35. |
2013
Kourrich S,Hayashi T#,Chuang JY#,Tsai SY,Su TP,Bonci A.
Dynamic interaction between Sigma-1 receptor and Kv1.2 shapes neuronal and behavioral responses to cocaine
. Cell
.2013
;(152):236-247
|
|
| 36. |
2012
Chuang JY,Wang SA,Yang WB,Hung CY,Su TP,Chang WC, Hung JJ.
Sp1 phosphorylation by cyclin-dependent kinase 1/cyclin B1 represses its DNA-binding activity during mitosis in cancer cells
. Oncogene
.2012
;(31):2946-4959
|
|
| 37. |
2011
Chuang JY,Chang WC,Hung JJ.
Hydrogen peroxide induces Sp1 methylation and thereby suppresses cyclin B1 via recruitment of Suv39H1 and HDAC1 in cancer cells
. Free Radic Biol Med
.2011
;(51):2309-2318
|
|
| 38. |
2011
Chuang JY,Hung JJ.
Overexpression of HDAC1 induces cellular senescence by Sp1/PP2A/pRb pathway
. Biochem Biophys Res Commun
.2011
;(407):587-592
|
|
| 39. |
2010
Chang LK,Chuang JY,Nakao M,Liu ST.
MCAF1 and synergistic activation of the transcription of Epstein-Barr virus lytic genes by Rta and Zta
. Nucleic Acids Res
.2010
;(38):4687-700
|
|
| 40. |
2009
Chuang JY,Wu CH,Lau MD,Chang WC,Hung JJ.
Overexpression of Sp1 leads to p53-dependent apoptosis in cancer cells
. Int J Cancer
.2009
;(125):2066-2079
|
|
| 41. |
2009
Wang SA,Chuang JY,Yeh SH,Wang YT,Liu YW,Chang WC, Hung JJ.
Heat shock protein 90 is important for Sp1 stability during mitosis
. J Mol Biol
.2009
;(387):1106-1119
|
|
| 42. |
2008
Wang YT,Chuang JY,Shen MR,Yang WB,Chang WC,Hung JJ.
Sumoylation of specificity protein 1 augments its degradation by changing the localization and increasing the specificity protein 1 proteolytic process
. J Mol Biol
.2008
;(380):869-885
|
|
| 43. |
2008
Chang LK,Liu ST,Kao CE,Wang WH,Chuang JY,Bianchi E, Hong YR.
Enhancement of transactivation activity of Rta of Epstein-Barr virus by RanBPM
. J Mol Biol
.2008
;(379):231-242
|
|
| 44. |
2008
Chuang JY,Wang YT,Yeh SH,Liu YW,Chang WC,Hung JJ.
Phosphorylation by c-Jun NH2-terminal kinase 1 regulates the stability of transcription factor Sp1 during mitosis
. Mol Biol Cell
.2008
;(19):1139-1151
|
|
| 45. |
2006
Liu ST,Wang WH,Hong YR,Chuang JY,Lu PJ,Chang LK.
Sumoylation of Rta of Epstein-Barr virus is preferentially enhanced by PIASxbeta
. Virus Res
.2006
;(119):163-170
|
|
| 46. |
2005
Chang LK,Chuang JY,Honh YR,Ichimura T,Nakao M,Liu ST.
Activation of Sp1-mediated transcription by Rta of Epstein-Barr virus via an interaction with MCAF1
. Nucleic Acids Res
.2005
;(33):6528-6539
|
|
| 47. |
2003
Chang LK,Wei TT,Chiu YF,Tung CP,Chuang JY,Hung SK, Li C, Liu ST.
Inhibition of Epstein–Barr virus lytic cycle by (−)-epigallocatechin gallate
. Biochem Biophys Res Commun
.2003
;(301):1062-1068
|
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