連立明(Lien, Li-Ming) 教授

Email
d102093012@tmu.edu.tw
現   職
神經學科 教授

學經歷

學 歷

畢業學校與學位[修業時間]
臺北醫學大學臨床醫學研究所 博士
93 ~2011
高雄醫學大學醫學系 學士
1982/09~1989/06

本校學術經歷

任職單位與職稱[起迄時間]
神經學科教授
2020/08/01~
神經學科副教授
2011/08/01~2020/07/31
神經學科助理教授
2007/08/01~2011/07/31

本校兼職教學行政經歷

服務單位與職稱[起迄時間]
無資料!

其它經歷

任職單位與職稱[起迄時間]
新光醫院 病歷管理委員會病歷品質審查醫師
2009/06/01~2010/05/31
臺灣腦中風學會理事
台灣腦中風學會秘書長
2007/03/18~2008/11/16
臺大醫學院 神經學科兼任講師
新光醫院 加護病房管理委員會委員
新光醫院 神經科加護病房主任
新光醫院神經內科主治醫師
1995/07/01~
台大醫院神經內科住院醫師
1991/07/01~1995/06/30

專長與研究領域

學門領域
神經內科學
腦血管疾病
粒線體疾病
學術專長

論文著作

清冊下載


1. 2023 Chen YC,Huang CY,Lien LM,Chen JH,Hsieh FI. Cardiovascular Toxicity of Angiogenesis Inhibitors Among Patients With Cancer in Taiwan: A Nested Case-Control Study . J Am Heart Assoc .2023

2. 2023 Yeh HL,Hsieh FI,Lien LM,Kuo WH,Jeng JS,Sun Y, Wei CY, Yeh PY, Yip HT, Lin CL, Huang N; Taiwan Stroke Registry Investigators. Patient and hospital characteristics associated with do-not-resuscitate/do-not-intubate orders: a cross-sectional study based on the Taiwan stroke registry . BMC Palliat Care .2023 ;(22):138:1-138:10

3. 2022 Ho LC,Wang HK,Chiu LT,Wang HH,Lee YC, Hung SY, Sun Y, Wei CY, Hsu KC, Chen YW, Lien LM, Hsu CY. Protein energy wasting-based nutritional assessment predicts outcomes of acute ischemic stroke and solves the epidemiologic paradox . Nutrition .2022

4. 2022 Wen CP,Lee YC,Sun YT,Huang CY,Tsai CH,Chen PL, Chang WL, Yeh PY, Wei CY, Tsai MJ, Sun Y, Lin CH, Lee JT, Lai TC, Lien LM, Lin MC, Lin CL, Lee JH, Wang HK, Hsu CY. Low-Density Lipoprotein Cholesterol and Mortality in Patients With Intracerebral Hemorrhage in Taiwan . Front Neurol .2022 ;(12)

5. 2022 Chen CH,Tang SC,Chen YW,Chen CH,Tsai LK,Sung SF, Lin HJ, Huang HY, Po HL, Sun Y, Chen PL, Chan L, Wei CY, Lee JT, Hsieh CY, Lin YY, Lien LM, Jeng JS. Effectiveness of Standard-Dose vs. Low-Dose Alteplase for Acute Ischemic Stroke Within 3-4.5 h . Front Neurol .2022

6. 2021 Lien LM,Lu WJ,Lin KH, Kang LH,Chen TY,Lin BJ, Lu YC, Huang CY, Shih CM, Chen H, Tsai YC, Chen RJ, Sheu JR. Influence of Vincristine, Clinically Used in Cancer Therapy and Immune Thrombocytopenia, on the Function of Human Platelets . Molecules .2021

7. 2021 Tsai LK,Lee IH,Chen YL,Chao TF, Chen YW,Po HL, Lien LM, Chu PH, Huang WC, Lin TH, Lin MT, Jeng JS, Hwang JJ. Diagnosis and Treatment for embolic stroke of undetermined source: Consensus statement from the Taiwan stroke society and Taiwan society of cardiology . J Formos Med Assoc .2021

8. 2020 Wang IK,Yen TH,Chen CH,Hsu SP,Sun Y,Lien LM, Chang WL, Lai TC, Chen PL, Chen CC, Huang PH, Lin CH, Su YC, Lin MC, Li CY, Sung FC, Hsu CY, Taiwan stroke registry investigators. Intravenous tissue plasminogen activator for acute ischemic stroke in patients with renal dysfunction . QJM .2020

9. 2020 Chiou HY,Bai CH,Lien LM,Hu CJ,Jeng JS,Tang SC, Lin HJ, Hsieh YC. Interactive Effects of a Combination of the HDAC3 and HDAC9 Genes with Diabetes Mellitus on the Risk of Ischemic Stroke . Thromb Haemost .2020

10. 2020 Lien LM,Lu WJ,Chen TY,Lee TY,Wang HH,Peng HY, Chen RJ, Lin KH. Phospholipase D1 and D2 Synergistically Regulate Thrombus Formation . Int J Mol Sci .2020

11. 2020 Chua SK,Hsieh FI,Hu CJ,Wang IK,Lee JT,Yeh HL, Lin KY, Lai TC, Sun Y, Jeng JS, Lin CL, Lien LM. Prognostic impact of renal dysfunction on embolic stroke of undetermined source-Role beyond CHA2 DS2 -VASc score: Results from Taiwan Stroke Registry . Eur J Neurol .2020

12. 2020 Lin CH,Hsu KC,Johnson KR,Fann YC,Tsai CH,Sun Y, Lien LM, Chang WL, Chen PL, Lin CL, Hsu CY. Evaluation of machine learning methods to stroke outcome prediction using a nationwide disease registry . Comput Methods Programs Biomed .2020

13. 2020 Hsia CH,Jayakumar T,Sheu JR,Hsia CW,Huang WC,Velusamy M, Lien LM. Synthetic Ruthenium Complex TQ-6 Potently Recovers Cerebral Ischemic Stroke: Attenuation of Microglia and Platelet Activation . J Clin Med .2020

14. 2020 Comparison of Arrhythmia Detection by 24-Hour Holter and 14-Day Continuous Electrocardiography Patch Monitoring. . Acta Cardiol Sin .2020

15. 2020 Yeh SJ,Tang SC,Tsai LK,Chen CH,Hsu SP,Sun Y, Lien LM, Wei CY, Lai TC, Chen PL, Chen CC, Huang PH, Lin CH, Liu CH, Lin HJ, Hu CJ, Lin CL, Jeng JS, Hsu CY, Taiwan Stroke Registry Investigators. Renal Function-Dependent Associations of Statins with Outcomes of Ischemic Stroke . J Atheroscler Thromb .2020

16. 2019 Qureshi AI,Qureshi MH,Lien LM,Lee JT,Jeng JS,Hu CJ, Lai TC, Liu CH, Chen CH, Chen PL, Chen TS, Li JY, Lin CL, Hsu CY, Taiwan Stroke Registry Investigators. One-Year Risk of Recurrent Stroke and Death Associated with Vertebrobasilar Artery Stenosis and Occlusion in a Cohort of 10,515 Patients . Cerebrovasc Dis .2019

17. 2019 Ma H,Campbell BCV,Parsons MW,Churilov L,Levi CR,Hsu C, Kleinig TJ, Wijeratne T, Curtze S, Dewey HM, Miteff F, Tsai CH, Lee JT, Phan TG, Mahant N, Sun MC, Krause M, Sturm J, Grimley R, Chen CH, Hu CJ, Wong AA, Field D, Sun Y, Barber PA, Sabet A, Jannes J, Jeng JS, Clissold B, Markus R, Lin CH, Lien LM, Bladin CF, Christensen S, Yassi N, Sharma G, Bivard A, Desmond PM, Yan B, Mitchell PJ, Thijs V, Carey L, Meretoja A, Davis SM, Donnan GA, EXTEND Investigators. Thrombolysis Guided by Perfusion Imaging up to 9 Hours after Onset of Stroke . N Engl J Med .2019

18. 2019 Chou CH,Lee JT,Tsai CK,Lien LM,Yin JH,Lin CC, Tsai IJ, Sung YF, Yang FC, Tsai CL, Wang IK, Tseng CH, Hsu CY. Increased risk of non-multiple sclerosis demyelinating syndromes in patients with preexisting septicaemia: a nationwide retrospective cohort study . Postgrad Med J .2019

19. 2019 Wang IK,Yen TH,Guo YC,Sun Y,Lien LM,Chang WL, Chen PL, Yang YC, Sung FC, Hsu CY, Taiwan Stroke Registry Investigators. Antiplatelet agents on the secondary prevention of ischemic stroke in patients with or without renal dysfunction . Eur J Neurol .2019

20. 2019 Chen YW,Sung SF,Chen CH,Tang SC,Tsai LK,Lin HJ, Huang HY, Po HL, Sun Y, Chen PL, Chan L, Wei CY, Lee JT, Hsieh CY, Lin YY, Yeh SJ, Lien LM*. Intravenous Thrombolysis Administration 3–4.5 h After Acute Ischemic Stroke: A Retrospective, Multicenter Study . Front Neurol .2019

21. 2019 Chen YW,Sung SF,Chen CH,Tang SC,Tsai LK,Lin HJ, Huang HY, Po HL, Sun Y, Chen PL, Chan L, Wei CY, Lee JT, Hsieh CY, Lin YY, Yeh SJ, Lien LM*, Jeng JS. Intravenous Thrombolysis Administration 3–4.5 h After Acute Ischemic Stroke: A Retrospective, Multicenter Study . Front Neurol .2019

22. 2019 Hsieh FI,Chiou HY,Hu CJ,Jeng JS,Lin HJ,Lee JT, Lien LM. Combined Effects of MMP-7, MMP-8 and MMP-26 on the Risk of Ischemic Stroke . J. Clin. Med .2019

23. 2018 Chen YR,Hsieh FI,Lien LM,Hu CJ,Jeng JS,Peng GS, Tang SC, Chi NF, Sung YF, Chiou HY. Rheumatoid arthritis significantly increased recurrence risk after ischemic stroke/transient ischemic attack . J Neurol .2018

24. 2018 Tsai CL,Lee JT,Lien LM,Lin CC,Tsai IJ,Sung YF, Chou CH, Yang FC, Tsai CK, Wang IK, Tseng CH, Hsu CY. The association between septicemia and the risk of multiple sclerosis: a nationwide register-based retrospective cohort study in Taiwan . QJM .2018

25. 2018 Chen WH,Yeh HL,Tsao CW,Lien LM,Chiu CC,Tseng MF, Huang LT, Lin KH. Plasma Translocator Protein Levels and Outcomes of Acute Ischemic Stroke: A Pilot Study. Dis Markers . Dis Markers .2018

26. 2018 Wang IK,Lien LM,Lee JT,Liu CH,Chen CH,Lin CH, Jeng JS, Hu CJ, Yen TH, Chen ST, Chiu HC, Tsai IJ, Sung FC, Hsu CY; Taiwan Stroke Registry Investigators. Renal dysfunction increases the risk of recurrent stroke in patients with acute ischemic stroke . Atherosclerosis .2018

27. 2018 Chen CH,Tang SC,Cheng YW,Tsai HH,Chi NF,Sung PS, Yeh HL, Lien LM, Lin HJ, Lee MJ, Hu CJ, Chiou HY, Jeng JS. Detrimental effects of intracerebral haemorrhage on patients with CADASIL harbouring NOTCH3 R544C mutation . J Neurol Neurosurg Psychiatry .2018

28. 2018 Chi NF,Wen CP,Liu CH,Li JY,Jeng JS,Chen CH, Lien LM, Lin CH, Sun Y, Chang WL, Hu CJ, Hsu CY, Taiwan Stroke Registry Investigators. Comparison Between Aspirin and Clopidogrel in Secondary Stroke Prevention Based on Real-World Data . J Am Heart Assoc .2018

29. 2018 Lu WJ,Chung CL,Chen RJ,Huang LT,Lien LM,Chang CC, Lin KH, Sheu JR. An Antithrombotic Strategy by Targeting Phospholipase D in Human Platelets . J Clin Med .2018

30. 2018 Tang SC,Chen YR,Chi NF,Chen CH,Cheng YW,Hsieh FI, Hsieh YC, Yeh HL, Sung PS, Hu CJ, Chern CM, Lin HJ, Lien LM, Peng GS, Chiou HY, Jeng JS. Prevalence and clinical characteristics of stroke patients with p.R544C NOTCH3 mutation in Taiwan . Ann Clin Transl Neurol .2018

31. 2017 Chang A,Hung HF,Hsieh FI,Chen WH,Yeh HL,Yeh JH, Chiu HC, Lien LM. Beneficial effects of prolonged blood pressure control after carotid artery stenting . Clin Interv Aging .2017 ;(12):103-109

32. 2017 Wang IK,Liu CH,Yen TH,Jeng JS,Sung SF,uang PH, Li JY, Sun Y, Wei CY, Lien LM, Tsai IJ, Sung FC, Hsu CY. Taiwan Stroke Registry Investigators.Renal function is associated with 1-month and 1-year mortality in patients with ischemic stroke . Atherosclerosis .2017 ;(S0021-9150)

33. 2017 Chang CC,Yeh HL,Hsiao CY,Lien LM. 10-Point CT-ASPECTS-based reperfusion therapy for unknown onset stroke . J Formos Med Assoc .2017 ;(S0929-6646)

34. 2017 Chang CC,Yeh HL,Hsiao CY,Lien LM. J Formos Med Assoc . 10-Point CT-ASPECTS-based reperfusion therapy for unknown onset stroke .2017 ;(S0929-6646):30677

35. 2017 Lien LM,Chiou HY,Yeh HL,Chiu SY,Jeng JS,Lin HJ, Hu CJ, Hsieh FI, Wei YH. Significant Association Between Low Mitochondrial DNA Content in Peripheral Blood Leukocytes and Ischemic Stroke . J Am Heart Assoc .2017 ;(6)

36. 2017 Wen CP,Liu CH,Jeng JS,Hsu SP,Chen CH,Lien LM, Chen AC, Lee JT, Chen PK, Hsu CS, Chern CM, Chen CC, Hsu MC, Lu K, Chen HJ, Wang HK, Muo CH, Hsu CY. Pre-stroke physical activity is associated with fewer post-stroke complications, lower mortality and a better long-term outcome. . Eur J Neurol .2017 ;(24):1525-1531

37. 2017 Pan WH,Lai YH,Yeh WT,Chen JR,Jeng JS,Bai CH, Lin RT, Lee TH, Chang KC, Lin HJ, Hsiao CF, Chern CM, Lien LM, Liu CH, Chen WH, Chang A. Intake of potassium- and magnesium-enriched salt improves functional outcome after stroke: a randomized, multicenter, double-blind controlled trial . Am J Clin Nutr .2017 ;(106):1267-1273

38. 2017 Lien LM,Lin KH,Huang LT,Tseng MF,Chiu HC,Chen RJ, Lu WJ. Licochalcone A Prevents Platelet Activation and Thrombus Formation through the Inhibition of PLCγ2-PKC, Akt, and MAPK Pathways . Int J Mol Sci .2017 ;(18)

39. 2017 Morotti A,Romero JM,Jessel MJ,Hernandez AM,Vashkevich A,Schwab K, Burns JD, Shah QA, Bergman TA, Suri MFK, Ezzeddine M, Kirmani JF, Agarwal S, Shapshak AH, Messe SR, Venkatasubramanian C, Palmieri K, Lewandowski C, Chang TR, Chang I, Rose DZ, Smith W, Hsu CY, Liu CL, Lien LM, Hsiao CY, Iwama T, Afzal MR, Cassarly C, Greenberg SM, Martin RH, Qureshi AI, Rosand J, Boone JM, Goldstein JN; ATACH-II and NETT Investigators. Phantom-based standardization of CT angiography images for spot sign detection . Neuroradiology .2017

40. 2017 Jeng JS,Hsieh FI,Yeh HL,Chen WH,Chiu HC,Tang SC, Liu CH, Lin HJ, Hsu SP, Lo YK, Chan L, Chen CH, Lin RT, Chen YW, Lee JT, Yeh CH, Sun MH, Lai TC, Sun Y, Sun MC, Chen PL, Chiang TR, Lin SK, Yip BS, Chen CI, Bai CH, Chen ST, Chiou HY, Lien LM*, Hsu CY; Taiwan Stroke Registry Investigators. Impact of MCA stenosis on the early outcome in acute ischemic stroke patients . PLoS One .2017 ;(12):e0175434-e0175434

41. 2017 Hsu CC,Chang HY,Wu IC,Chen CC,Tsai HJ,Chiu YF, Chuang SC, Hsiung WC, Tsai TL, Liaw WJ, Lin IC, Shen SC, Juan CC, Lien LM, Lee M, Chen YI, Liu K, Hsiung CA. Cohort Profile: The Healthy Aging Longitudinal Study in Taiwan (HALST) . Int J Epidemiol .2017

42. 2017 Hsieh YC,Hsieh FI,Chen YR,Hu CJ,Jeng JS,Tang SC, Chi NF, Lin HJ, Lien LM, Peng GS, Chiou HY; Formosa Stroke Genetic Consortium (FSGC). Associations of estradiol levels and genetic polymorphisms of inflammatory genes with the risk of ischemic stroke . J Biomed Sci .2017 ;(24)

43. 2017 Wang IK,Liu CH,Yen TH,Jeng JS,Hsu SP,Chen CH, Lien LM, Lin RT, Chen AC, Lin HJ, Chi HY, Lai TC, Sun Y, Lee SP, Sung SF, Chen PL, Lee JT, Chiang TR, Lin SK, Muo CH, Ma H, Wen CP, Sung FC, Hsu CY; Taiwan Stroke Registry Investigators. Cholesterol Levels Are Associated with 30-day Mortality from Ischemic Stroke in Dialysis Patients . J Stroke Cerebrovasc Dis. .2017 ;(26):1349-1356

44. 2016 Lien LM,Wang MJ,Chen RJ,Chiu HC,Wu JL,Shen MY, Chou DS, Sheu JR, Lin KH, Lu WJ. Nobiletin, a Polymethoxylated Flavone, Inhibits Glioma Cell Growth and Migration via Arresting Cell Cycle and Suppressing MAPK and Akt Pathways . Phytother Res .2016 ;(30):214-221

45. 2016 Chua SK,Wang BW,Lien LM,Lo HM,Chiu CZ,Shyu KG. Mechanical Stretch Inhibits MicroRNA499 via p53 to Regulate Calcineurin-A Expression in Rat Cardiomyocytes . PLoS One .2016 ;(11):e01486

46. 2016 Hsieh FI,Jeng JS,Chern CM,Lee TH,Tang SC,Tsai LK, Liao HH, Chang H, LaBresh KA, Lin HJ, Chiou HY, Chiu HC, Lien LM. Quality Improvement in Acute Ischemic Stroke Care in Taiwan: the Breakthrough Collaborative in Strok . PLoS One .2016 ;(11):e01604

47. 2016 Chua SK,Shyu KG,Lin YF,Lo HM,Wang BW,Chang H, Lien LM. Tumor Necrosis Factor-Alpha and the ERK Pathway Drive Chemerin Expression in Response to Hypoxia in Cultured Human Coronary Artery Endothelial Cells . PLoS One .2016 ;(11):e01656

48. 2015 Chung CL,Leung KW,Lu WJ,Yen TL,He CF,Sheu JR, Lin KH, Lien LM. Hinokitiol Negatively Regulates Immune Responses through Cell Cycle Arrest in Concanavalin A-Activated Lymphocytes . Evid Based Complement Alternat Med .2015

49. 2015 Jeng JS,Sun Y,Lee JT,Lin RT,Chen CH,Po HL, Lin HJ, Liu CH, Sun MH, Sun MC, Chern CM, Lien LM, Chiu HC, Hu HH, Chiou HY, Chen ST, Ma H, H. The efficacy and safety of cilostazol in ischemic stroke patients with peripheral arterial disease (SPAD): protocol of a randomized, double-blind, placebo-controlled multicenter trial. . Int J Stroke .2015 ;(10):123-127

50. 2015 Tang SC,Yeh SJ,Tsai LK,Hu CJ,Lien LM,Peng GS, Yang WS, Chiou HY, Jeng JS. Cleaved but not endogenous secretory RAGE is associated with outcome in acute ischemic stroke . Neurology .2015

51. 2014 Tang SC,Yeh SJ,Tsai LK,Hu CJ,Lien LM,Peng GS, Yang WS, Chiou HY, Jeng JS.. J Neuroinflammation . Association between plasma levels of hyaluronic acid and functional outcome in acute stroke patients .2014 ;(11):101

52. 2014 Yen TL,Lu WJ,Lien LM,Thomas PA,Lee TY,Chiu HC, Sheu JR, Lin KH.. Amarogentin, a Secoiridoid Glycoside, Abrogates Platelet Activation through PLC γ 2-PKC and MAPK Pathways. . Biomed Res Int. .2014 ;(2014)

53. 2014 Lien LM,Chen ZC,Chung CL,Yen TL,Chiu HC,Chou DS, Huang SY, Sheu JR, Lu WJ, Lin KH.. Multidrug resistance protein 4 (MRP4/ABCC4) regulates thrombus formation in vitro and in vivo. . Eur J Pharmacol .2014 ;(737):159-167

54. 2013 Lien LM,Su CC,Hsu WH,Lu WJ,Chung CL,Yen TL, Chiu HC, Sheu JR, Lin KH.. Mechanisms of Andrographolide-Induced Platelet Apoptosis in Human Platelets: Regulatory Roles of the Extrinsic Apoptotic Pathway . Phytother Res .2013

55. 2013 Yen TL,Hsu WH,Huang SK,Lu WJ,Chang CC,Lien LM, Hsiao G, Sheu JR, Lin KH.. A novel bioactivity of andrographolide from Andrographis paniculata on cerebral ischemia/reperfusion-induced brain injury through induction of cerebral endothelial cell apoptosis. . Pharm Biol. .2013 ;(51):1150-1157

56. 2013 Chua SK,Shyu KG,Lu MJ,Lien LM,Lin CH,Chao HH, Lo HM.. Clinical utility of CHADS2 and CHA2DS2-VASc scoring systems for predicting postoperative atrial fibrillation after cardiac surgery. . J Thorac Cardiovasc Surg .2013 ;(146):919-926

57. 2013 Yeh HL,Chen YK,Chen WH,Wang HC,Chiu HC,Lien LM*, Wei YH.. Perfusion status of the stroke-like lesion at the hyperacute stage in MELAS. . Brain Dev .2013 ;(35):158-164

58. 2013 Olaiya MT,Chiou HY,Jeng JS,Lien LM,Hsieh FI. Significantly Increased Risk of Cardiovascular Disease among Patients with Gallstone Disease: A Population-Based Cohort Study. . PLoS One .2013 ;(8):e76448

59. 2013 Lien LM,Su CC,Hsu WH,Lu WJ,Chung CL,Yen TL, Chiu HC, Sheu JR, Lin KH. Mechanisms of Andrographolide-Induced Platelet Apoptosis in Human Platelets: Regulatory Roles of the Extrinsic Apoptotic Pathway. . Phytother Res .2013 ;(27):1671-1677

60. 2012 Hsieh YC,Lien LM,Chung WT,Hsieh FI,Hsieh PF,Wu MM, Tseng HP, Chiou HY, Chen CJ.. Significantly increased risk of carotid atherosclerosis with arsenic exposure and polymorphisms in arsenic metabolism genes . Environ Res .2012 ;(111):804-810

61. 2012 Wu MM,Chiou HY,Chen CL,Hsu LI,Lien LM,Wang CH, Hsieh YC, Wang YH, Hsueh YM, Lee TC, Cheng WF. Association of heme oxygenase-1 GT-repeat polymorphism with blood pressure phenotypes and its relevance to future cardiovascular mortality risk: An observation based on arsenic-exposed individuals. . Atherosclerosis .2012

62. 2012 Yeh SJ,Jeng JS,Tang SC,Liu CH,Hsu SP,Chen CH, Lien LM, Lin HJ, Chen CM, Lin RT, Lee SP, Lin CH, Yeh CH, Sun Y, Sun MH, Yin JH, Lin CC, We. Taiwan Stroke Registry Investigators. Low estimated glomerular filtration rate is associated with poor outcomes in patients who suffered a large artery atherosclerosis stroke . Atherosclerosis .2012 ;(239):328-334

63. 2012 Lien LM,Su CC,Hsu WH,Lu WJ,Chung CL,Yen TL, Chiu HC, Sheu JR, Lin KH.. Mechanisms of Andrographolide-Induced Platelet Apoptosis in Human Platelets: Regulatory Roles of the Extrinsic Apoptotic Pathway. . Phytotherapy Research .2012

64. 2012 Hsieh YC,Jeng JS,Lin HJ,Hu CJ,Yu CC,Lien LM, Peng GS, Chen CI, Tang SC, Chi NF, Tseng HP, Chern CM, Hsieh FI, Bai CH, Chen YR, Chiou HY.. Epistasis analysis for estrogen metabolic and signaling pathway genes on young ischemic stroke patients. . PLoS One .2012 ;(7):e4777

65. 2012 Lee YM,Hsieh KH,Lu WJ,Chou HC,Chou DS,Lien LM, Sheu JR, Lin KH. anthohumol, a Prenylated Flavonoid from Hops (Humulus lupulus), Prevents Platelet Activation in Human Platelets. . Evid Based Complement Alternat Med. .2012 ;(2012):852362

66. 2012 Yeh HL,Chen YK,Chen WH,Wang HC,Chiu HC,Lien LM*, Wei YH. Perfusion status of the stroke-like lesion at the hyperacute stage in MELAS. . Brain Dev .2012

67. 2011 Shyu KG,Lien LM,Wang BW,Kuan P,Chang H. Resistin contributes to neointimal formation via oxidative stress after vascular injury. . Clin Sci (Lond) .2011 ;(120):121-129

68. 2011 Hsieh YC,Lien LM,Chung WT,Hsieh FI,Hsieh PF,Wu MM, Tseng HP, Chiou HY, Chen CJ.. Significantly increased risk of carotid atherosclerosis with arsenic exposure and polymorphisms in arsenic metabolism genes. . Environ Res. .2011 ;(111):804-810

69. 2011 Chou CC,Lien LM,Chen WH,Wu MS,Lin SM,Chiu HC, Chiou HY, Bai CH.. Adults with late stage 3 chronic kidney disease are at high risk for prevalent silent brain infarction: a population-based study. . Stroke. .2011 ;(42):2120-5

70. 2010 Hsieh FI,Lien LM,Chen ST,Bai CH,Sun MC,Tseng HP, Chen YW, Chen CH, Jeng JS, Tsai SY, Lin HJ, Liu CH, Lo YK, Chen HJ, Chiu HC, Lai ML. Taiwan Stroke Registry Investigators. Get With the Guidelines-Stroke performance indicators: surveillance of stroke care in the Taiwan Stroke Registry: Get With the Guidelines-Stroke in Taiwan. . Circulation .2010 ;(122):1116-1123

71. 2010 Lin TK,Lien LM,Chen WH,Huang SJ,Su CL. A concise guideline for the management of large hemispheric infarction in taiwan: 2010 update: a guideline from the taiwan stroke society. . Acta Neurol Taiwan. .2010 ;(19):297-303

72. 2010 Chung N,Jeon HK,Lien LM,Lai WT,Tse HF,Chung WS, Lee TH, Chen SA.. Safety of edoxaban, an oral factor Xa inhibitor, in Asian patients with non-valvular atrial fibrillation. . Thromb Haemost. .2010 ;(105)

73. 2010 Lien LM,Hsieh YC,Bai CH,Chen WH,Chiu HC,Hsieh FI, Shyu KG, Chiou HY, Hsu CY.. Association of blood active matrix metalloproteinase-3 with carotid plaque score from a community population in Taiwan. . Atherosclerosis. .2010 ;(212):595-600

74. 2010 Hsieh FI,Lien LM,Chen ST,Bai CH,Sun MC,Tseng HP, Chen YW, Chen CH, Jeng JS, Tsai SY, Lin HJ, Liu CH, Lo YK, Chen HJ, Chiu HC, Lai ML, Lin R. AHA/ASA Get With The Guidelines-Stroke Performance Indicators: Surveillance of Stroke Care in the Taiwan Stroke Registry. . Circulation .2010 ;(122):1116-1123

75. 2010 Wu MM,Hsieh YC,Lien LM,Chen WH,Bai CH,Chiu HC, Chen HH, Chung WT, Lee YC, Hsu CY, Lin HW, Chiou HY.. Association of Estrogen Receptor a Genotypes/Haplotypes With Carotid Intima-Media Thickness in Taiwanese Women. . Angiology. .2010 ;(61):275-282

76. 2010 Wu MM,Chiou HY,Chen CL,Wang YH,Hsieh YC,Lien LM, Lee TC, Chen CJ.. GT-repeat polymorphism in the heme oxygenase-1 gene promoter is associated with cardiovascular mortality risk in an arsenic-exposed population in northeastern Taiwan . Toxicol Appl Pharmacol .2010 ;(248):226-233

77. 2010 Lau CI,Lien LM,Chen WH. Brainstem Hyperperfusion Syndrome After Intravenous Thrombolysis: A Case Report. . J Neuroimaging .2010 ;(19):297-230

78. 2010 Hsieh YC,Hwang LC,Hsieh FI,Lien LM,Lin HJ,Hu CJ, Tseng HP, Bai CH, Chiou HY.. Early Menarche and Ischemic Stroke Risk among Postmenopausal Women . Int J Gerontol .2010 ;(4):16-22

79. 2009 Hsieh YC,Hung CT,Lien LM,Bai CH,Chen WH,Yeh CY, Chen YH, Hsieh FI, Chiu HC, Chiou HY, Hsu CY.. A significant decrease in blood pressure through a family-based nutrition health education programme among community residents in Taiwan . Public Health Nutr .2009 ;(12):570-577

80. 2009 Wu MM,Hsieh YC,Lien LM,Chen WH,Bai CH,Chen HH, Chung WT, Lee YC, Hsu CY, Lin HW, Chiou HY.. Association of Estrogen Receptor {alpha} Genotypes/Haplotypes With Carotid Intima-Media Thickness in Taiwanese Women. . Angiology .2009

81. 2009 Hsieh FI,Lo WC,Lin HJ,Hsieh YC,Lien LM,Bai CH, Tseng HP, Chiou HY.. Significant synergistic effect of peroxisome proliferator-activated receptor gamma C-2821T and diabetes on the risk of ischemic stroke. . Diabetes Care .2009 ;(32):2033-2035

82. 2009 Chuang SY,Bai CH,Chen WH,Lien LM,Pan WH. Fibrinogen independently predicts the development of ischemic stroke in a Taiwanese population: CVDFACTS study. . Stroke. .2009 ;(40):1578-1584

83. 2008 Hsieh YC,Hsieh FI,Lien LM,Chou YL,Chiou HY,Chen CJ. Risk of carotid atherosclerosis associated with genetic polymorphisms of apolipoprotein E and inflammatory genes among arsenic exposed residents in Taiwan. . Toxicol Appl Pharmacol .2008 ;(227):1-7

84. 2008 Lin YW,Lien LM,Yeh TS,Wu HM,Liu YL,Hsieh RH. 9-cis retinoic acid induces retinoid X receptor localized to the mitochondria for mediation of mitochondrial transcription. . Biochem Biophys Res Commun. .2008 ;(377):351-354

85. 2008 Hsieh YC,Hung CT,Lien LM,Bai CH,Chen WH,Yeh CY,Chen YH, Hsieh FI, Chiu HC, Chiou HY, Hsu CY.. A significant decrease in blood pressure through a family-based nutrition health education programme among community residents in Taiwan. . Public Health Nutr. .2008 ;(19):1-8

86. 2007 Chen WH,Bai CH,Huang SJ,Chiu HC,Lien LM. Outcome of large hemispheric infarcts: an experience of 50 patients in Taiwan. . Surg Neurol. .2007 ;(68):S68-S73

87. 2007 Hsu YF,Lien LM,Lin CH,Hung CR. Vertebral-subclavian steal syndrome—report of a case. . Chirurgia .2007 ;(20):81-83

88. 2006 Huang SJ,Chen YS,Hong WC,Chang L,Han YY,Kao MC, Lien LM, Tu YK.. Clinical experience of hydroxyethyl starch (10% HES 200/0.5) in cerebral perfusion pressure protocol for severe head injury. . Surg Neurol .2006 ;(66):26-31

89. 2006 Hong WC,Wang YK,Chen YS,Lien LM,Kao MC,Huang SJ. Subdural intracranial pressure monitoring in severe head injury: Clinical experience with Codman Microsensor. . Surg Neurol .2006 ;(66):8-13

90. 2006 Lien LM,Chen WH,Chiu HC,Pan WH,Chen JR,Bai CH. High Titer of Anticardiolipin Antibody Is Associated with First-Ever Ischemic Stroke in Taiwan. . Cerebrovasc Dis. .2006 ;(22):225-230

91. 2006 Schminke U,Motsch L,Lien LM,Tan TY,Bond MG,Toole JF, Tegeler CH.. Screening for High-grade Carotid Stenosis Using a Portable Ultrasonography Instrument. . J Neuroimaging. .2006 ;(16):252-259

92. 2006 Wang YH,Wu MM,Hong CT,Lien LM,Hsieh YC,Tseng HP, Chang SF, Su CL, Chiou HY, Chen CJ.. Effects of arsenic exposure and genetic polymorphisms of p53, glutathione S-transferase M1, T1, and P1 on the risk of carotid atherosclerosis in Taiwan. . Atherosclerosis. .2006 ;(192):305-312

93. 2005 Yen CY,Lien LM,Shieh JS,Chen WH,Chiu HC. Cerebrovascular Response to Different Stimulations and Patterns in Healthy Volunteers. . Journal of Medical and Biological Engineering. .2005 ;(25):185-191

94. 2005 Hsieh RH,Lien LM,Lin SH,Chen CW,Cheng HJ,Cheng HH. Alleviation of oxidative damage in multiple tissues in rats with streptozotocin-induced diabetes by rice bran oil supplementation. . Ann N Y Acad Sci .2005 ;(1042):365-371

95. 2005 Chua CH,Lien LM,Lin CH,Hung CR. Emergency surgical intervention in a patient with delayed diagnosis of aortic dissection presenting with acute ischemic stroke and undergoing thrombolytic therapy. . J Thorac Cardiovasc Surg .2005 ;(130):1222-1224

研究計畫

計畫名稱
98 高血壓盛行率調查與血壓之影響因子分析計畫-以臺北市政府員工為例
補助單位
台北市政府衛生局